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Judgment & ambiguity · Calibrating confidence

A routine sterilization load comes back with a single positive biological indicator, though all physical cycle parameters were nominal. How confident are you that the lot is sterile, and how do you decide whether it can be released?

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I start honest: a single positive BI means I cannot claim this lot is sterile, and nominal cycle parameters don't override a biological result — the BI is the direct evidence.

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